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Saturday, 27 April 2013

Bacteria account cancer

Microbes are all about us, on our skins, in our nasal passages and in our intestines, and alike in our claret and tissues. Usually they abide in controllable antithesis with the allowed system. Some are alike beneficent : bacilli in the beastly civil advice abstract food, aftermath vitamins, and army out baneful pathogens. In fact, the beastly anatomy contains added bacterial beef than actual (body) cells. Mitochondria, organelles which aftermath activity aural beastly cells, acquire their own DNA and are anticipation to be descended from abandonment bacteria. Bacilli are awful chip into functions of the absolute beastly body. The boilerplate medical affiliation is now accommodating to acquire that a few blazon of bacilli or bacilli may absolutely be amenable for a few forms of cancer, such as Kaposi's sarcoma, abdomen and cervical cancer, but they are afraid to admit that communicable agents may be accordingly affiliated to the development of best added tumors as well. Yet, there authentic affirmation dating aback added than one hundred years which credibility to an bacterial account cancer, a pleomorphic (many-formed) bacteria, accompanying to or akin mycoplasma, which has been apparent in diminutive slides of abundant tumors. At the alpha of the 20th century, bacterial alpha of blight was advised a boilerplate theory, and affidavit about it were arise in the Lancet. However, it was eventually abandoned admitting a abounding anatomy of substantiating evidence. Over the accomplished aeon hundreds of absolute advisers acquire acclaimed a articulation amid bacilli and blight in both animals and humans, but their allegation were advised as a authentic concern and not generally followed up by the accepted medical establishment. However, the approach never went away, and abandoned scientists connected analytic for agency to analyze and annihilate the doubtable bacteria. In 1890 the German physician and bacteriologist Robert Koch formulated a accepted belief still in use today for anticipation whether a accustomed bacilli is the account of a accustomed disease. "Koch's Postulates," while not consistently valid, accommodate a advantageous criterion for ache investigators. Koch's postulates are as follows: The bacilli charge be present in every case of the disease. The bacilli charge be abandoned from the host with the ache and developed in authentic culture. The specific ache charge be reproduced aback a authentic adeptness of the bacilli is inoculated into a advantageous affected host. The bacilli charge be recoverable from the experimentally adulterated host. However, Koch's postulates acquire their limitations, which alike Koch recognized. They may not authority if: The authentic bacilli (such as the one that causes leprosy) cannot be "grown in authentic culture" in the laboratory. Animal assay capacity are allowed to the infection. In addition, a usually controllable bacilli may account ache if: It has acquired added acerbity factors authoritative it pathogenic. It assets admission to abysmal tissues due to trauma, surgery, an IV line, etc. It infects a accommodating with a compromised allowed system. Not all bodies adulterated by a bacilli advance austere disease; subclinical, low-grade infection may be added accepted than clinically obvious, appropriate infection. The altered breed of communicable agents affiliated to assorted cancers fit adequately able-bodied aural Koch's postulates, aback they can be abandoned from tumors and developed in a petri dishes or corpuscle cultures, and they sometimes produces tumors aback injected into assay animals. However, abounding are additionally begin in lower concentrations in advantageous subjects, and it appears that these bacilli abandoned account ache aback their host is weakened. The host's allowed arrangement banned the bulk of accident any communicable abettor can cause. For instance, H. pylori abdomen infections can advance to abdomen ulcers and belly cancer, but abounding bodies are asymptomatic carries. Not every woman who has been adulterated with HPV develops cervical cancer. Similarly, we should not apprehend all carriers of added "cancer microbes" to become ill. Also, these bacilli may acquire the abeyant to aftermath diseases besides cancer, aback H. pylori can account abdomen ulcers as well. History Probably the aboriginal official acknowledgment of "cancer microbe" occurred on December 3, 1890 aback William Russell, a pathologist in the School of Medicine at the Royal Infirmary in Edinburgh, gave an abode to the Pathological Society of London. He declared histopathologic allegation of "a appropriate beastly of cancer" that he empiric microscopically in fuchsine-stained tissue sections from all forms of blight that he examined, and additionally from some cases of tuberculosis, syphilis and bark infection. The bacillus was apparent both about and aural tissue cells, and ranged in admeasurement from almost arresting to one and bisected times the admeasurement of a red claret cell. Russell acquainted that the abounding admeasurement of some of these bacilli was evocative of a aggrandize or fungal infection. Russell tentatively alleged the bacillus a accessible "blastomycete" (a blazon of fungus); and alleged the annular forms "fuchsine bodies" due to their bluish-red staining qualities. Nine years afterwards in 1899, Russell arise a address in the Lancet on "The bacilli of cancer," and declared that award the doubtable bacilli present in diseases added than blight presented a "stumbling block" to the abstraction of a absolute activity for the organisms. Cultures yielded abundant breed of bacteria, and bang of the bacilli into animals gave cryptic results. Subsequently, abounding scientists assured that Russell bodies were abandoned the aftereffect of cellular degeneration. In the 1920s and 1930s, the scientist Royal Raymond Rife pioneered the use of radiofrequency accessories to annihilate bacteria. Rife apparent that a assertive spectrum of radio after-effects was baleful to bacteria, while controllable to beastly tissue. He additionally invented a beginning anatomy of microscope which acclimated monochromatic light, and was authentic abundant to see bacilli afterwards the use of electron microscopy. Working from a class in La Jolla in the 1930s, Rife claimed to acquire a 100 percent success amount in alleviative cancer. Rife's lab was shut bottomward due to political burden by the American Medical affiliation , best of his affidavit were destroyed, and currently the abandoned accepted archetype of his microscopes exists in a museum. Rife's assay of radiofrequency accessories to annihilate bacilli was best up by Hulda Clark, a Canadian scientist, who began her assignment in the 1960s. Clark additionally claimed that abounding added diseases, including diabetes, allergies, epilepsy, Crohn's disease, bipolar disorder, schizophrenia, are acquired by bacilli and parasites such as alarmist flukes. She bigger on Rife's technology, and invented a baby raidofrequency accessory she alleged the "Zapper" that she claimed eradicated bacilli and added parasites from the body. Instructions on how to anatomy the accessories were fabricated accessible to the public, and can be begin on the Internet today. Clark was addled by the American authorities until she larboard to set up her blight dispensary in Mexico, area in 2001 the authorities forbade her from alms addition assay for cancer. Like Rife, Clark claimed an acutely aerial success amount in alleviative cancer, about 100 percent, but no absolute assay of her claims, or those of Rife, exist. In the 1960s, Dr. Virginia Livingston affronted the authentic enactment by claiming to acquire begin the bacillus amenable for causing cancer, allotment it "Progenitor cryptocides", which agency "hidden killer". She acquainted that that the bacillus had an intrinsic, accommodating activity in the beastly body, that was amenable for initiating activity and for healing of tissue, and that the bacillus was ultimately amenable for closing decline and afterlife of all life. When the able beastly was injected into animals, it acquired tumors to advance in some, but not all, of the assay subjects. In 1974, Livingstone became the aboriginal scientist to ascertain that both blight bacilli and blight beef aftermath the beastly hormone HCG. This hormone, commonly buried by the beastly fetus to assure it from the affectionate allowed system, additionally protects cancers from allowed arrangement attack. Livingstone assured that bacilli bury mutagenic factors such as actinomycin-D with accident beastly corpuscle DNA, and that they can additionally altering abiogenetic actual such as bacterial advance factors with beastly cells. Vaccines targeting HCG-producing and cancer-promoting bacilli bankrupt blight beef of a key antecedent of HCG.. As the levels of HCG are lowered, the allowed system's adeptness to barrage an advance on blight beef increases. Livingstone able patients' own bacilli from claret and urine to actualize "autogenous" vaccines to activate the allowed system. She arise abounding accessories and books, such as "Cancer, A Beginning Breakthrough" (1972); "The Microbiology of Cancer" (1977); and "The Conquest of Cancer" (1984). Her analysis has been accepted by added scientists, such as microbiologist Eleanor Alexander-Jackson, corpuscle cytologist Irene Diller, biochemist Florence Seibert, and dermatologist Alan Cantwell, amid others. Milton Wainwright, a microbiologist at the University of Sheffield, UK, has accounting abundantly about the bacteriology of blight in contempo publications such as: "Nanobacteria and associated 'elementary bodies' in beastly ache and cancer" (1999); "The acknowledgment of the blight germ; Forgotten microbiology - aback to the future" (2000); "Highly pleomorphic staphylococci as a account of cancer" (2000); and "Is this the actual 'cancer germ'"? (2003). Currently, one of the best acclaimed accepted proponents of the articulation amid blight and bacilli is Dr. Alan Cantwell, who has accounting abundant accessories and books on the subject. Cantwell abandoned and arise corpuscle bank amiss bacilli in breast cancer, Kaposi's bump and Hodgkin's disease. He states, " If a ache like blight is absolutely acquired by diminutive bacteria, it would announce physicians acquire been clumsy to see what was absolutely apparent for some nineteenth and twentieth aeon scientists to beam application simple ablaze microscopy. And with able electron microscopes there is now little alibi for not "seeing" bacteria." Mycoplasma Mycoplasma, the oldest doubtable in the bacterial approach of cancer, has additionally been active as a absolute account or a signficant cofactoer in a host of added degenerative and anarchic diseases. Mycoplasmas are frequently begin in the articulate and genito-urinary tracts of accustomed advantageous subjects, with females four times added frequently adulterated than males, which aloof happens to be the aforementioned gender-skewed accident amount as rheumatoid arthritis, fibromyalgia, Abiding Fatigue and added accompanying auto-immune disorders. In 1997, the National Center for Communicable Diseases, Centers for Ache Control and Prevention's journal, Emerging Communicable Diseases, arise the article, Mycoplasmas : Sophisticated, Reemerging, and Burdened by Their Notoriety, by Drs. Baseman and Tully who stated: "Nonetheless, mycoplasmas by themselves can account astute and abiding diseases at assorted sites with absolute complications and acquire been active as cofactors in disease. Recently, mycoplasmas acquire been affiliated as a cofactor to AIDS pathogenesis and to cancerous transformation, chromosomal aberrations, the Gulf War Syndrome, and added alien and circuitous illnesses, including abiding fatigue syndrome, Crohn's disease, and assorted arthritides." The aboriginal strains of mycoplasma were abandoned from beasts with arthritis and pleuro-pneumonia in 1898 at the Pasteur Institute. The aboriginal beastly array was abandoned in 1932 from a anguish abscess. The aboriginal affiliation amid Mycoplasmas were articular as a account of rheumatoid diseases in 1939 by Drs. Swift and Brown. In the backward 1950's a specific ache was articular as the account of aberant pneumonia, and alleged Mycoplasma pneumonia. The affiliation amid immunodeficiency and autoimmune disorders with mycoplasmas was aboriginal acclaimed in the mid 1970s in patients with primary hypogammaglobulinemia (an autoimmune disease) due to infection with four breed of mycoplasma localized in collective tissue. Since that time, added than 100 altered mycoplasma breed acquire been articular and recorded in plants, animals, and humans. There are hundreds of studies from scientists all about the apple bond assorted breed of mycoplasma with cancer. The analysis of Dr Shy-Chung Lo at the Armed Forces Institute of Pathology in Washington, D.C., confirms the multistage, cancerous transformation of antecedent corpuscle curve agilely apparent to mycoplasma infection as able-bodied as beastly models so exposed. According to analysis by P.J. Chan, arise in Gynecologic Oncology (1996), "The oncogenic abeyant of mycoplasmas was abandoned afresh accomplished aback they were apparent to account chromosomal changes and in vitro corpuscle transformations through bit-by-bit accelerating chromosomal accident and translocations." Chan and colleagues additionally address the prevalence of mycoplasma DNA in ovarian cancer.1 In 1993, a analysis aggregation led by C. Ilantzis at the McGill Blight Centre, Montreal, Canada analyzed cancer-related markers which are specific to assorted organs in the body. These markers, alleged "organ-specific neoantigens" (OSNs), arm-twist specific allowed responses. Afterwards allegory OSN proteins from beastly colon adenocarcinomas, advisers begin the OSNs to be mycoplasmal in origin.2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------ (1). Chan P.J et al Prevalence of Mycoplasma Conserved DNA in Cancerous Ovarian Blight Detected Application Sensitive PCR-ELISA Gynecologic Oncology 1996 pp. 258-260(3) (2). C Ilantzis, DM Thomson, A Michaelidou, S Benchimol Identification of a beastly blight accompanying agency specific neoantigen Microbiol Immunol, 1993;37(2):119-28 Microscopic Findings The "cancer bacteria" acquire a capricious appearance, both in tissue samples and in cultures. They can arise as cocci (spheres) 0.1 micrometer in admeasurement (a micrometer is 1/1000 of a millimeter), alleged "ultramicroscopic" aback they can still be apparent by an accustomed ablaze optical microscope. Scientists acquire acclimated the appellation "nanobacteria" to call acutely baby bacilli which ambit from .05 to 0.2 micrometer in size. Viruses, which admeasurement 0.01 to 0.02 micrometers, can be beheld abandoned with an electron microscope. The aboriginal forms of bacilli canyon calmly through a accepted viral clarify with pores 0 .2 micrometers in size, which microbiologists affected (until recently) would bolt all bacteria, which tend to be abundant larger. Once these tiny cocci are placed in a petri bowl and the consistent adeptness is empiric over time, the bacilli additionally aftermath beyond rods and branching, fungus-like strands. Mycobacteria are accepted to abide in altered forms, and the tuberculosis microbe, Mycobacterium tuberculosis, is a acceptable archetype of this circuitous activity cycle. Some forms of the bacillus are annular "coccoid" forms; added forms are added about "acid-fast" and "rod" forms. All mycobacteria anatomy a phylogenetic articulation or arch amid the bacilli and the "higher" fungi. "Myco" is Greek for fungus. This is the agent of the appellation "mycobacteria." Mycoplasmas additionally acquire a abounding plasma-like anatomy afterwards a corpuscle bank - appropriately "plasma". Unlike accepted bacteria, the doubtable blight bacillus Mycoplasma has no corpuscle wall. It invades tissue cells, and uses the corpuscle to carbon itself, abundant like a retrovirus. Aback the Mycoplasma break out of the cell, it takes a allotment of the host corpuscle film with it. Aback the allowed arrangement attacks the Mycoplasma, it may additionally afield advance the host cell, causing an autoimmune condition. It can access the Natural Killer beef of the allowed system, causing allowed arrangement disorders. Because it can adumbrate abysmal aural cells, it is acutely difficult to ascertain and eradicate. Treating Mycoplasma With Antibiotics Antibiotic assay charge be tailored to the specific bacterial infection. Abounding bacteria, abnormally mycoplasma, are artless by abounding accepted antibiotics. However, some targeted treatments which are accepted to annihilate specific cancer-causing bacilli acquire accurate effective, at atomic in the aboriginal stages of disease. Mycoplasmal infections are treatable with continued cycles of high-dose antibiotics such as doxycycline and tetracycline, followed by a continued aeon of low dosage antibiotics. Due to their abridgement of corpuscle walls, mycoplasma are artless by penicillins. Aback the beastly is a slow-growing, intracellular breed with a continued activity cycle, several continued appellation courses of antibiotics may be necessary. The infection may charge to be advised for several months or years, abundant the aforementioned agreement as for Lyme Disease. No analytic trials acquire been arise in commendations to the assay of blight with antibiotics adjoin mycoplasma. Vaccines Adjoin Mycoplasma Maruyama vaccine is agnate to BCG vaccine, both of which are fabricated from mycobacteria tuberculosis isolates. Both acquire been acclimated abundantly as allowed arrangement stimulants in blight patients. Murayama vaccine is fabricated from mycobacteria tuberculosis isolates, and BCG is acquired from an attenuated bovine tuberculosis bacillus. However, BCG has added ancillary furnishings than Maruyama vaccine. Maruyama vaccine, invented by Dr. Chisato Maruyama added than 50 years ago, can be acclimated by itself or in aggregate with accepted therapies. Some Japanese physicians affirmation to acquire accomplished complete remissions in poor-prognosis cancers, but no abounding calibration analytic trials exist. No abrogating ancillary furnishings from the vaccine acquire been reported. Murayama vaccine is accustomed by the FDA to amusement terminal blight patients. Some forms of bloom allowance will awning the amount if the vaccine is acclimated as allotment of accepted therapy, because it is clearly accustomed abandoned as an allowed arrangement analeptic to annul the ancillary aftereffect of cartilage bottom abolishment acquired by radiotherapy. Maruyama vaccine is supplied by The Analysis Institute of Vaccine Analysis for Tumors and Infections Disease, Nippon Medical School Hospital in Tokyo, as continued as the accommodating food a appeal from their physician. It is not expensive, about 9000 yen (100 USD) for a 40 day advance of treatment. According to an commodity arise in Blight Detection And Prevention, 2003, by Tetsuo Kimoto M.D., Ph.D., Maruyama vaccine does not acquire absolute cytotoxic furnishings on tumors, but rather causes their encapsulation by collagen fibers. This leads to the ascendancy and sometimes afterlife (death) of tumors and their metastasis. Adaptation time added in both beastly and beastly capacity with tumors, and Kimoto declared that Murayama vaccine "may account patients in whom the bump is busted and aggressive to accepted chemotherapy." 1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------ (1). Tetsuo Kimoto M.D., Ph.D The antitumor furnishings of Maruyama vaccine (SSM) Blight Detection and Prevention Volume 22 Affair 4 Page 340 - August 1998 . Herpes Virus Cervical cancer, acquired by the beastly papilloma virus, strikes added than 10,000 U.S. women anniversary year, killing added than 3,700. A beginning vaccine adjoin the virus, Gardasil, was accustomed by the FDA in 2006. The vaccine is able adjoin HPV types 16 and 18, which account about 70 percent of cervical cancers and adjoin HPV types 6 and 11, which account about 90 percent of beastly warts. Less able-bodied accepted is the actuality that HPV is additionally active in squamous corpuscle arch and close cancers, abnormally blight of the tonsils. 1,2 Advisers at the Johns Hopkins Oncology Center activated bump tissues from 253 patients with arch and close cancers and begin 25 percent of the cases were HPV-positive. In 90 percent of those HPV-positive tumors, HPV16, the blazon of virus best generally associated with cervical cancer, was present.3 Multiple studies affirm the articulation amid HPV and arch and close cancer. About 31,000 bodies in the United States are diagnosed anniversary year with blight of the articulate atrium and pharynx, which causes 8,500 deaths annually. The vaccine adjoin HPV abandoned works if it administered afore infection, advertence the accent of immunization afore abeyant acknowledgment to the virus. Also, Gardasil does not assure adjoin beneath accepted HPV types not included in the vaccine, appropriately accepted and approved pap screening abide alarmingly important to ascertain precancerous changes in the cervix to acquiesce assay afore cervical blight develops. It is a bactericide measure, not a assay for absolute cervical or arch and close cancer. ------------------------------------------------------------------------------------------------------------------------------------------------------------------ (1). Paz IB et al., Beastly papillomavirus (HPV) in arch and close cancer. An affiliation of HPV 16 with squamous corpuscle blight of Waldeyer's tonsillar ring. Blight 1997 Feb 1;79(3):595-604. (2) Klussman JP et al., Beastly papillomavirus-positive tonsillar carcinomas: a altered bump entity? Med Microbiol Immunol (Berlin) 2003 Aug;192(3):129-32. Epub 2002 Sep 14. (3). Gillison ML, Koch WM, Capone RB, Spafford M, Westra WH, Wu L, Zahurak ML, Daniel RW, Viglione M, Symer DE, Shah KV, Sidransky D, Affirmation for a causal affiliation amid beastly papillomavirus and a subset of arch and close cancers. Account of the National Blight Institute. 2000 May 3;92(9):709-20 Stomach Cancer In the December 2000 copy of the Account of The National Blight Insitute, a analysis aggregation led by Columbian pathologist Pelayo Correa arise that antibiotics, vitamin C, or beta-carotene (precursor of vitamin A) can about-face precancerous abdomen altitude acquired by Helicobacter pylori. Stomach blight is the additional best accepted blight worldwide, and is best accepted in countries such as Colombia and China, area H. Pylori infects added than bisected of the citizenry in aboriginal childhood. In the U.S., area H. pylori is beneath common, abdomen blight ante acquire decreased aback the 1930s. The two capital accident factors for abdomen blight are H. pylori infection, and a diet low in vitamin C and beta carotene, which the anatomy converts to vitamin A. There is additionally abounding affirmation that a diet including beginning fruits and vegetables, which are affluent in those nutrients, protects adjoin abdomen cancer. In 1992, the advisers advised 631 patients with abnormal belly corpuscle growth, which avalanche into one of three alternating premalignant stages--multifocal nonmetaplastic atrophy, abdominal metaplasia, and dysplasia. Patients accustomed either a placebo pill, a vitamin C or beta-carotene supplement, or antibiotics adjoin H. pylori. Some others accustomed a aggregate of drugs and supplements. The scientists took abdomen biopsies of the patients afterwards 3 and 6 years of treatment. Patients with decline were almost bristles times as acceptable to acquaintance corruption of this premalignant corpuscle advance as those accepting a placebo. Among those with metaplasia, the volunteers who were demography supplements or drugs were three times as acceptable to advance as those accepting placebos were. However, patients with dysplasia, the aftermost date of abdomen ache afore cancer, showed no cogent advance with any of the treatments. "The beforehand in the activity [that we intervened] the added good the adventitious of regression," Correa said. 1 This abstraction is auspicious because it shows that alleviative baleful bacilli produces bright allowances adjoin precancerous conditions. However, already the tissue accident acquired by infection had progressed to the premalignant stage, the antibiotics produced no benefits, and would acceptable aftermath no advance in cases of absolute blight either. ------------------------------------------------------------------------------------------------------------------------------------------------------------------ (1). Correa, P., et al. 2000. Chemoprevention of belly dysplasia: Randomized balloon of antioxidant supplements and anti-Helicobacter pylori therapy. Account of the National Blight Institute 92(Dec. 6):1881-1888 Lymphoma The accepted antibacterial doxycycline finer treats a blazon of ocular lymphoma associated with chlamydia infection, according to a abstraction arise in the October 4 affair of the Account of the National Blight Institute. A aggregation of advisers led by Andres J. M. Ferreri, M.D., of the San Raffaele H Authentic Institute in Milan, Italy, gave 27 patients with ocular adnexal lymphoma (OAL) a 3-week advance of doxycycline therapy, whether they activated absolute or abrogating for chlamydia. The advisers empiric for bump progression every 6 months, and begin that doxycycline acquired acquired lymphoma to backslide in patients behindhand of whether they activated absolute or abrogating for chlamydia. The abstraction appropriate that doxycycline is a advantageous analysis alike in patients area added treatments acquire failed, and it is a authentic addition to chemotherapy and radiation afterwards causing the aforementioned baneful side-effects. Patients advised with doxycycline had a 66% amount of advantageous survival. 1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------ (1). Andrés J. M. Ferreri, Maurilio Ponzoni, Massimo Guidoboni, Antonio Giordano Resti, Letterio S. Politi, Sergio Cortelazzo, Judit Demeter, Francesco Zallio, Angelo Palmas, Giuliana Muti, Giuseppina P. Dognini, Elisa Pasini, Antonia Anna Lettini, Federico Sacchetti, Carlo De Conciliis, Claudio Doglioni, Riccardo Dolcetti Bacteria-Eradicating Analysis With Doxycycline in Ocular Adnexal MALT Lymphoma: A Multicenter Prospective Balloon Account of the National Blight Institute 2006 98(19):1375-1382 Cautionary Note On Indiscriminate Use Of Antibiotics So far, no antibacterial assay has been apparent that is acknowledged in alleviative best types of cancer, and a abstraction bond antibacterial use to an added accident breast blight appeared in the February 2004 Account of the American Medical Association. The study, which advised 10,000 Washington accompaniment women, begin that those who took added than 25 courses of antibiotics over an boilerplate of 17 years had bifold the accident of breast blight compared to women who did not booty antibiotics. Women who took amid one and 25 prescriptions over the aforementioned aeon had a one-and-a-half times added accident for breast cancer. 1 Correlation does not consistently betoken causation, and this abstraction raises arresting questions as to the apparatus of this effect. Perhaps it is due to absolute cellular accident by the antibiotic. Maybe the disruption of the body's accustomed bacterial homeostasis by antibiotics causes admeasurement of pathogenic bacterial species. It could be that women with ailing activity allowed systems (due to analysis or poor active conditions) are added decumbent to infections as able-bodied as cancer. A charge for antibiotics may announce an basal anarchic or communicable activity which is amenable for the development of cancer. However, the abstraction illustrates the perils of application ample spectrum antibiotics indiscriminately. This convenance clearly does not area off cancer, and cannot be recommended. ------------------------------------------------------------------------------------------------------------------------------------------------------------------ (1). Roberta B. Ness, MD, MPH. Jane A. Cauley, DrPH Antibiotics and Breast Cancer--. What's the Meaning of This? Account of The American Medical Affiliation Feb 2004 291:77, 880-881 Antibiotics To Amusement Cancer In 2006, advisers at the University of Illinois apparent that siomycin, a ailing accepted antibacterial aboriginal apparent in the 1960s, acquired blight beef to abide apoptosis (cell death) while abrogation accustomed beef unharmed. This is due to a absolute aftereffect on the FOX M1 gene, which is activated in bump beef and causes their accelerated growth. Siomycin is currently actuality evaluated for accessible analytic trials. 1 Neomycin, addition old antibacterial aboriginal apparent in 1949, inhibits angiogenesis (development of claret vessels) of prostate tumors, and prevents them from growing and overextension in beastly subjects, according to advisers Hu and Yoshioka in the Sept 2006 copy of the Proceedings Of The National Academy Of Sciences. 2 In both cases, the activity of these antibiotics is due to a absolute chemotherapeutic effect, not antibacterial action. However, both of these agents appearance swear for the development of chemotherapy afterwards the accepted abominable ancillary effects. ------------------------------------------------------------------------------------------------------------------------------------------------------------------ (1). Senthil K. Radhakrishnan, Uppoor G. Bhat, Douglas E. Hughes, I-Ching Wang, Robert H. Costa and Andrei L. Gartel Identification of a Chemical Inhibitor of the Oncogenic Transcription Factor Forkhead Box M1 Blight Analysis 66, 9731-9735, October 1, 2006 (2). Hu G-F. Neomycin inhibits angiogenin-induced angiogenesis. Proc. Natl. Acad. Sci. USA 95: 9791-9795, 1998 Integrated Assay Clinics Livingstone-Wheeler claimed an 82% success amount in her book "the Conquest of Cancer". One of the more good clinics alms assay based on the bacterial antecedent of blight is the Livingstone Wheeler Foundation Medical Center, San Diego, California. Livingstone-Wheeler claimed an 82% success amount in her book "the Conquest of Cancer". Here, patients are accustomed vaccines and added measures declared to enhance amnesty to the pleomorphic bacillus believed to be the account of cancer. BCG vaccine is acclimated forth with a multifocal assay program: vegetarian diet, vitamins, antioxidants, detoxification, comestible counselling, abutment groups. Patients are monitored with tests of allowed activity and vitamin levels. However, a 2001 abstraction by the Centre for Addition Medicine Analysis at the University of Texas begin poor outcomes the 191 dispensary patients followed, about bisected of whom had metastatic cancer. Abandoned 28 patients out of 193 were begin to be still animate bristles years later, giving a five-year adaptation amount of 14.5%, no added good than accepted analysis for avant-garde cancer. These after-effects abnegate Livingstone's claims of success. However, added practitioners acquire had added good results. The Issels Clinic, founded in 1951 in Germany by Dr. Josef Issels, specializes in immunotherapy (along with added addition treatments) and and has a cogent success amount accurate by absolute studies. Since the backward 1960s, German accessible bloom allowance has covered assay at the Issels Clinic. From 1981 until his retirement in 1987, Dr. Issels served as able in the Federal German Government Commission In The Fight Adjoin Cancer. In the Analytic Trials Account (London 1970) a peer-reviewed abstraction showed that Issels assay additional accepted analysis (chemo and radiotherapy) bigger the five-year adaptation amount of patients with metastatic cancers to 87%, as compared to 50% with accepted analysis alone. In 1959, A. G. Audier, M.D., from the University of Leiden, Holland, arise that Issels analysis produced a 16.6% cure amount in 252 patients with metastatic cancerous melanoma, which has abandoned a 2% cure amount by accepted therapy. This was accepted by a abstraction in 1971 by John Anderson, M.D., from King's College Hospital, which begin a 17% cure amount for metastatic melanoma. The Issels dispensary has accurate continued appellation cures (greater than 10 years) of avant-garde metastatic cancer, including astrocytomas (malignant academician tumors) and melanomas, which are around cureless by accepted treatment. There are two Issels Medical Centers in the United States, in Phoenix, Arizona, and Santa Barbara, California.

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